甲苯二异氰酸酯生成过程中间副产物结构的确定

The Intermediate Structure in the Production of Tolylene Diisocyanate

摘要: 在重要有机化工原料甲苯二异氰酸酯的生产过程中经常会产生一些非目标中间体,严重地影响反应进程.确定这些中间副产物的结构对研究反应机理、改进反应条件具有极其重要的意义.采用核磁共振一维及二维HMBC技术确定了该反应中的副产物结构,特别对用其它分析方法难以确定的其苯环取代基的位置进行了准确定位.

Abstract: Tolylene diisocyanate is a more important organic compound, and by-products always be produced during its production. It is necessary to determine the structure of the by-product, for the research of the reaction mechanism and reaction condition. A method is described whereby the structure of the byproducts, especially the substitute radical can be determined by ¹H, ¹³C and HMBC spectrum.