Abstract: An open and comprehensive experiment has been designed. The microwave-assisted Fenton method is used to perform the degradation decoloring treatments of reactive red 2. The ultraviolet spectral analysis, infrared spectral analysis and determination of chemical oxygen demand were carried out before and after the degradation. This experiment involves the knowledge and operations in the fields of instrumental analysis, dye chemistry, environmental engineering, etc., which helps the middle and senior students to integrate the knowledge they learned, so as to enhance the students' innovative consciousness and ability.