Abstract: The measurement of the dissolving amount of lead and cadmium in domestic ceramics and the principle of standard curve method are summarized. The dissolution of heavy metals are tested through the extract of different concentrations and its dilute under each respective standard curves. Using the single factor level variance analysis method (F test) to verify the significant difference level of the result data, and probe into the reason of the formation of difference according to the Lambert Beer law. Under the condition of confidence level of 95%,when the lead concentration of sample solution is lower than 80.0 mg/L and cadmium concentrations is lower than 1.000 mg/L, no significant difference appeared between the test result data of original samples extract solution and its dilute solution, when the lead concentration of sample solution is more than 100.00 mg/L and cadmium concentrations is more than 1.000 mg/L, there is no the significant difference between the test result data of original sample extract solutions and its dilute solution increase with the higher concentrations of heavy metal elements.